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Showing 1–16 of 16 results
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  • Record-high ocean temperatures, combined with a confluence of extreme climate and weather patterns, are pushing the world into uncharted waters. Researchers must help communities to plan how best to reduce the risks.

    • Alistair J. Hobday
    • Michael T. Burrows
    • Thomas Wernberg
    Comments & Opinion
    Nature
    Volume: 621, P: 38-41

  • In a finding that could have implications for vaccine design, memory immune cells at mucosal surfaces have been shown to respond to encounters with pathogens by issuing signals that recruit other memory cells to the site.

    • Jennifer E. Smith-Garvin
    • Luis J. Sigal
    News & Views
    Nature
    Volume: 497, P: 194-196

  • Greenland's glaciers have lost significant amounts of ice over the past decade. Rediscovered historical images of the ice margin show a record of southeast Greenland's response to the last major warming event in the 1930s.

    • Benjamin E. Smith
    News & Views
    Nature Geoscience
    Volume: 5, P: 369-370

  • The demonstration that diamond nitrogen–vacancy centre technology can optically detect voltages with an impressive sensitivity could bring new opportunities for investigating neurobiology.

    • Milos Nesladek
    • Micha E. Spira
    News & Views
    Nature Photonics
    Volume: 16, P: 675-677

  • This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes.

    • Sarah E. Smith
    • Rachael S. Wash
    News
    Nature Reviews Microbiology
    Volume: 11, P: 150

    • Richard E. T. Smith
    • Mona Ashiya
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 6, P: 597-598

  • Minimal hepatic encephalopathy (MHE)—the mild cognitive impairment commonly seen in patients who have cirrhosis—has a significant impact on quality of life. Current understanding is that MHE forms part of the spectrum of hepatic encephalopathy, although this remains to be proven. This Review focuses on the pathogenesis and neuropsychological findings of MHE, the effect of MHE on quality of life and survival, and treatment options.

    • Charmaine A Stewart
    • Glenn E Smith
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 4, P: 677-685

  • This Review provides a comprehensive and contemporary overview of the interleukin-1 (IL-1) family: their expression and regulation, their effects on innate immune cells, their regulation of adaptive immune responses and their roles in immune-mediated diseases.

    • John E. Sims
    • Dirk E. Smith
    Reviews
    Nature Reviews Immunology
    Volume: 10, P: 89-102

  • Adult mammalian CNS axons show little regenerative capacity following injury, in part because they fail to assemble functional growth cones at their tips. However, axons from the mammalian peripheral nervous system and non-mammalian species show more regenerative potential. Here, Bradkeet al. examine the process of growth cone assembly after axonal injury. Understanding why this process does not always succeed may facilitate the development of treatments for CNS-damage-related disability.

    • Frank Bradke
    • James W. Fawcett
    • Micha E. Spira
    Reviews
    Nature Reviews Neuroscience
    Volume: 13, P: 183-193

  • The majority of patients with cancer do not die as a result of the primary tumour, rather from the metastases that arise from that tumour. The mechanisms and markers of metastasis have, therefore, been a main focus of both clinical and preclinical research. This Perspectives article discusses the hurdles that need to be overcome to successfully translate the preclinical metastasis research into the clinic.

    • François-Clément Bidard
    • Jean-Yves Pierga
    • Jean Paul Thiery
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 10, P: 169-179