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Showing 1–6 of 6 results
Advanced filters: Author: "Edward A Fisher" Clear advanced filters

  • Triglyceride-rich lipoproteins (TRLs) transport lipid calories to tissues that need energy, but TRLs can also contribute to obesity and vascular disease. A newly discovered pathway shows how cold exposure increases the uptake and combustion of TRLs by brown adipose tissue, thereby correcting harmful hyperlipidemias (pages 200–205).

    • Kevin Jon Williams
    • Edward A Fisher
    News & Views
    Nature Medicine
    Volume: 17, P: 157-159

  • Given the high risk of sudden death or myocardial infarction associated with atherosclerosis, frequently with no previous symptoms, techniques to better identify high-risk plaques might help lower morbidity and mortality. In this review, various biological markers are suggested as targets for imaging to aid risk assessment.

    • Michael J Lipinski
    • Valentin Fuster
    • Zahi A Fayad
    Reviews
    Nature Clinical Practice Cardiovascular Medicine
    Volume: 1, P: 48-55

  • In this Review, the authors provide a comprehensive overview of the role of macrophage dynamics in determining the initiation, progression and regression of atherosclerotic inflammation. Understanding the factors that determine the inflammatory state of the plaque may help to identify potential therapeutic targets for plaque regression.

    • Kathryn J. Moore
    • Frederick J. Sheedy
    • Edward A. Fisher
    Reviews
    Nature Reviews Immunology
    Volume: 13, P: 709-721

  • Inflammatory processes are central to the development and complications of atherosclerosis and acute myocardial infarction. In this Review, Ruparelia et al. summarize the inflammatory pathways involved in these cardiovascular diseases, highlight contemporary techniques to characterize and quantify inflammation, and consider how they might be used to guide specific treatments.

    • Neil Ruparelia
    • Joshua T. Chai
    • Robin P. Choudhury
    Reviews
    Nature Reviews Cardiology
    Volume: 14, P: 133-144

  • Rapid stabilization and regression of atherosclerosis, even for advanced complex plaques, has been achieved experimentally in both animals and humans. In this insightful Review, Kevin Williams, Jonathan Feig and Edward Fisher examine the successes and failures of many established and experimental interventions to induce plaque regression, and discuss how regression of atheromata could become a realistic therapeutic goal.

    • Kevin Jon Williams
    • Jonathan E Feig
    • Edward A Fisher
    Reviews
    Nature Clinical Practice Cardiovascular Medicine
    Volume: 5, P: 91-102