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Showing 1–3 of 3 results
Advanced filters: Author: "Ellis L. Reinherz" Clear advanced filters

  • T-cell receptors orchestrate immune-system responses against infection and cancer. A structure of an entire T-cell receptor complex clarifies its assembly and signalling, and sheds light on its dynamic ligand recognition.

    • Ellis L. Reinherz
    News & Views
    Nature
    Volume: 573, P: 502-504

  • A drug used for HIV treatment can alter the set of antigens that activates T cells of the immune system, thereby triggering life-threatening reactions against the body's own proteins. See Letter p.554

    • Ellis L. Reinherz
    News & Views
    Nature
    Volume: 486, P: 479-481

  • The success and pathogenicity of HIV-1 largely resides in the function of the viral protein Nef. Here, the authors propose that Nef modulates a T cell's ability to form an immunological synapse and modulates T-cell activation to favour viral replication and spread.

    • Oliver T. Fackler
    • Andres Alcover
    • Olivier Schwartz
    Reviews
    Nature Reviews Immunology
    Volume: 7, P: 310-317