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Showing 1–2 of 2 results
Advanced filters: Author: "Emily P. Balskus" Clear advanced filters

  • Potent microbial toxins found in shellfish are possible starting points for drug discovery, but analogues are needed for biological testing. Toxin-modification enzymes now suggest a new approach for producing these analogues.

    • Monica E. McCallum
    • Emily P. Balskus
    News & Views
    Nature
    Volume: 570, P: 315-316

  • The gene cluster that produces the sponge-derived cytotoxin calyculin A has been located in an uncultivated bacterial symbiont. Biochemical analyses reveal a pyrophosphorylated protoxin as the true biosynthetic product and suggest that calyculins result from activated chemical defense.

    • Emily P Balskus
    News & Views
    Nature Chemical Biology
    Volume: 10, P: 611-612