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Showing 1–5 of 5 results
Advanced filters: Author: "Emmanouil T Dermitzakis" Clear advanced filters

  • The author discusses the advantages and challenges of 'cellular phenotyping' and the way in which this integrated analysis of cellular phenotypes is likely to advance our understanding of the genetic and long-term environmental influences on complex traits.

    • Emmanouil T. Dermitzakis
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 215-220

  • Gene expression can be an indicator of cellular state, and studies characterizing variation in gene expression have been useful on the cellular level. Two new studies now provide the first direct demonstration of the successful use of the multidimensionality of gene expression to dissect the genetic architecture of complex diseases.

    • Emmanouil T Dermitzakis
    News & Views
    Nature Genetics
    Volume: 40, P: 492-493

  • The authors describe how the evolving designs of eQTL studies, facilitated by advances in genotyping and gene-expression-based technologies, are increasingly able to investigate the role of regulatory variation in different biological contexts.

    • Stephen B. Montgomery
    • Emmanouil T. Dermitzakis
    Reviews
    Nature Reviews Genetics
    Volume: 12, P: 277-282