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Showing 1–4 of 4 results
Advanced filters: Author: "Eran Halperin" Clear advanced filters

  • Only a subset of genetic variants can be examined in genome-wide surveys for genetic risk factors. How can a fixed set of markers account for the entire genome by acting as proxies for neighboring associations?

    • Eran Halperin
    • Dietrich A Stephan
    Reviews
    Nature Biotechnology
    Volume: 27, P: 255-256

  • Only a subset of single-nucleotide polymorphisms (SNPs) can be genotyped in genome-wide association studies. Imputation methods can infer the alleles of 'hidden' variants and use those inferences to test the hidden variants for association.

    • Eran Halperin
    • Dietrich A Stephan
    Reviews
    Nature Biotechnology
    Volume: 27, P: 349-351

  • The increased genetic diversity in populations with recent ancestry from more than one continent may help in the identification of genetic variants underlying disease risk. This Progress article discusses recent developments in methods to study complex traits in these admixed populations, including combining SNP and admixture association signals.

    • Michael F. Seldin
    • Bogdan Pasaniuc
    • Alkes L. Price
    Reviews
    Nature Reviews Genetics
    Volume: 12, P: 523-528