Polymyalgia rheumatica (PMR) is an inflammatory disorder of unknown aetiology that can be extremely disabling when active. Glucocorticoids are currently the therapy of choice for patients with PMR, but responsiveness to treatment varies considerably. The identification of different morphological patterns of disease defined by distinct extracapsular or capsular-based inflammation might, at least in part, explain this variability in responses to treatment.
- Frank Buttgereit
- Eric L. Matteson