Rheumatoid arthritis (RA) is increasingly recognized as a risk factor for cardiovascular disease, independent of the presence of classic cardiovascular risk factors such as smoking and obesity. In this article, the authors review the pathophysiology of accelerated atherosclerosis in RA, and discuss the potential role of statins in the reduction of both inflammation and atherosclerosis in these patients.
- Radjesh J. Bisoendial
- Erik S. G. Stroes
- Paul Peter Tak