Universal immunization against HBV and blood-donor screening for HBV and HCV have greatly decreased the risk of transmission of these viruses; however, a significant number of children still become chronically infected with HBV and HCV. In this Review, the authors consider the epidemiology, transmission, prevention, clinical presentation and natural history, management and screening, and treatment of hepatitis B and C in children.
- Evelyn K Hsu
- Karen F Murray