Francesco Cucca, Serena Sanna, David Schlessinger, Gonçalo Abecasis and colleagues report genome-wide association analysis results for the levels of A1, A2 and fetal hemoglobin in a large Sardinian cohort. By integrating high-density array genotyping and whole-genome sequencing, they detect 23 associations at 10 loci and observe a wide range of pleiotropic effects of variants across the 3 hemoglobin types.
- Fabrice Danjou
- Magdalena Zoledziewska
- Francesco Cucca
