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Showing 1–4 of 4 results
Advanced filters: Author: "Fabrice Lavial" Clear advanced filters

  • Reprogramming holds great promise for regenerative medicine but the molecular mechanisms governing the generation of induced pluripotent stem cells remain unclear. Here, the authors reveal functions for the axonal guidance cue Netrin-1 in constraining apoptosis at the early stage of reprogramming and in established pluripotent cells.

    • Duygu Ozmadenci
    • Olivier Féraud
    • Fabrice Lavial
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-11

  • During development the embryo must balance lineage specification against the preservation of plasticity using a limited molecular toolkit. In this Perspective, the authors propose Molecular Versatility as a paradigm for grouping molecular mechanisms that are repurposed through development to exert distinct functions.

    • Giacomo Furlan
    • Aurélia Huyghe
    • Fabrice Lavial
    ReviewsOpen Access
    Nature Communications
    Volume: 14, P: 1-13