All women, regardless of ethnicity, geographic location or culture will transition through perimenopause. Many of the neurological symptoms that emerge during this transition are the result of estrogen depletion in the brain. In this Review, the authors discuss the neurological symptoms associated with perimenopause in the context of estrogen-mediated processes in the brain.
- Roberta D. Brinton
- Jia Yao
- Enrique Cadenas