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Showing 1–4 of 4 results
Advanced filters: Author: "Francois Lallemend" Clear advanced filters

  • Programmed cell death is an important part of tissue development, and traditionally it is considered that neuronal death is a stochastic process in response to neurotrophic factor deprivation. Here the authors show that for TrkC+ proprioreceptors, which neurons die is predetermined molecularly by how much TrkC is present, as well as by a gene expression signature.

    • Yiqiao Wang
    • Haohao Wu
    • François Lallemend
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Spiral ganglion neurons (SGNs) of the cochlea receive input from hair cells and project to the auditory brainstem. Here, the authors perform single-cell RNA sequencing to identify four SGN subclasses and characterize their molecular profile, electrophysiological properties and connectivity.

    • Charles Petitpré
    • Haohao Wu
    • François Lallemend
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Molecular diversity of proprioceptive neuron types (Ia, Ib and II PNs) is unclear. Here, the authors characterized the functional organization and development of eight subtypes of PNs in mice. Importantly, Ia subtypes are plastic, suggesting a role in adaptive proprioception during motor behavior.

    • Haohao Wu
    • Charles Petitpré
    • François Lallemend
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13