Many drugs are used to treat colorectal cancer but there is little information about how predictive factors can be used to improve treatment response and reduce toxic effects related to anticancer treatment. The authors of this Review analyse the main data in this investigation field, and highlight the most important predictive factors that relate to toxic effects in patients with colorectal cancer who are treated with anticancer chemotherapy, both in adjuvant and in advanced setting.
- Bruno Vincenzi
- Gaia Schiavon
- Giuseppe Tonini