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Showing 1–2 of 2 results
Advanced filters: Author: "Gabriel Lopez-Berestein" Clear advanced filters
  • MicroRNAs (miRNAs) is an exciting and fast-moving field in cancer diagnosis and therapeutics. This Review highlights the use of circulating miRNAs in body fluids as a noninvasive diagnostic tool and as a treatment-response predictor. It also explores the concept that body-fluid-based miRNAs possibly originated as the first 'hormones'.

    • Maria Angelica Cortez
    • Carlos Bueso-Ramos
    • George A. Calin
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 8, P: 467-477
  • Inherent difficulties with blocking many desirable targets using conventional approaches have prompted many to consider using RNA interference (RNAi) as a therapeutic approach. This Review explores current challenges to the development of synthetic RNAi-based therapies and considers new approaches to circumvent biological barriers.

    • Chad V. Pecot
    • George A. Calin
    • Anil K. Sood
    Reviews
    Nature Reviews Cancer
    Volume: 11, P: 59-67