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Showing 1–4 of 4 results
Advanced filters: Author: "Georg Schlieper" Clear advanced filters
  • Calcific uremic arteriolopathy (CUA), a condition associated with high mortality, is most common among patients on dialysis. In this opinion article, Georg Schlieper and his colleagues discuss the evidence on the efficacy of administering sodium thiosulfate in the treatment of CUA. Given the lack of large clinical trials, the authors also evaluate the consultation of internet-accessible CUA case registries as a strategy to inform the treatment of this disease and to design future studies.

    • Georg Schlieper
    • Vincent Brandenburg
    • Jürgen Floege
    Reviews
    Nature Reviews Nephrology
    Volume: 5, P: 539-543
  • Aspirin and other antiplatelet agents are widely used in patients with chronic kidney disease. However, their use is often based on data obtained in patients with normal renal function. A recent Cochrane Collaboration systematic review analysed the benefits and risks of these agents in patients with chronic kidney disease.

    • Jürgen Floege
    • Georg Schlieper
    News & Views
    Nature Reviews Nephrology
    Volume: 9, P: 314-316
  • Extraosseous calcifications are highly prevalent in patients with chronic kidney disease. Several pathological mechanisms of extraosseous calcification have been identified, which might serve as therapeutic targets. The authors of this Review describe some of the processes involved in calcification, including the role of calciprotein particles, osteogenic transdifferentiation and vitamin K. They also discuss promising agents for the treatment of extraosseous calcification and present some of the questions that remain.

    • Markus Ketteler
    • Hansjörg Rothe
    • Georg Schlieper
    Reviews
    Nature Reviews Nephrology
    Volume: 7, P: 509-516