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Showing 1–5 of 5 results
Advanced filters: Author: "George Thomas" Clear advanced filters
  • Causal associations have been established between dysregulated ribosome biogenesis and cancer. In this Opinion article, the authors highlight emerging mechanistic data on the molecular basis of ribosomes in cancer and offer their perspective on how these advances present therapeutic opportunities.

    • Joffrey Pelletier
    • George Thomas
    • Siniša Volarević
    Reviews
    Nature Reviews Cancer
    Volume: 18, P: 51-63
  • A genome-wide characterization of active translation of messenger RNA following inhibition of mTOR will transform our view of this signalling protein's regulatory role in cancer. See Article p.55 & Letter p.109

    • Antonio Gentilella
    • George Thomas
    News & Views
    Nature
    Volume: 485, P: 50-51
  • Cells sense and respond to physical stresses through mechanotransduction, a process that converts mechanical stimuli into biochemical signals. The bending of primary cilia has now been shown to modulate TOR signalling to negatively regulate cell size.

    • Brian M. Wiczer
    • Adem Kalender
    • George Thomas
    News & Views
    Nature Cell Biology
    Volume: 12, P: 1031-1033