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Showing 1–4 of 4 results
Advanced filters: Author: "George Vande Woude" Clear advanced filters

  • Signalling through the receptor tyrosine kinase MET and its ligand hepatocyte growth factor/scatter factor (HGF/SF) has been associated with various types of cancer, which has led to numerous efforts to try and target these proteins. This Review discusses HGF/SF–MET signalling in cancer and current progress with targeting this pathway.

    • Ermanno Gherardi
    • Walter Birchmeier
    • George Vande Woude
    Reviews
    Nature Reviews Cancer
    Volume: 12, P: 89-103

    • Carmen Birchmeier
    • Walter Birchmeier
    • George F. Vande Woude
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 4, P: 915-925

  • BAP1 is a deubiquitylase that is associated with multiprotein complexes that regulate key cellular pathways. Recent findings have indicated that germlineBAP1mutations might cause a novel cancer syndrome. Michele Carbone and colleagues discuss the evidence for this.

    • Michele Carbone
    • Haining Yang
    • Giovanni Gaudino
    Reviews
    Nature Reviews Cancer
    Volume: 13, P: 153-159