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Showing 1–6 of 6 results
Advanced filters: Author: "Gerhard Rogler" Clear advanced filters

  • Treatment of the chronic disease ulcerative colitis is impeded by systemic side effects of orally administered drugs. Here the authors develop a gel that uses the rectal temperature as a mechanism to trigger solidification for localized delivery of colitis therapeutics.

    • Marianna Carone
    • Marianne R. Spalinger
    • Simone Aleandri
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • An international consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease has recently been published. The statement is an important starting point to address the many problems we still have with the clinical classification and treatment of fistulising Crohn's disease.

    • Gerhard Rogler
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 11, P: 581-583

  • A central role is proposed for the gastrointestinal tract in graft-versus-host disease (GvHD) because the occurrence ofNOD2/CARD15mutations in the gut can predict severe GvHD. These findings could influence current therapeutic strategies for GvHD and Crohn's disease and change our understanding of their pathophysiology.

    • Gerhard Rogler
    • Ernst Holler
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 1, P: 62-63

  • A considerable proportion of patients with Crohn's disease are affected by the formation of fistulas, and appropriate fistula treatment requires knowledge of the available medical therapies. This Review discusses the pharmacological and surgical approaches available for the treatment of fistulas in patients with Crohn's disease, including novel therapeutic approaches. Discussion of the epidemiology and pathology of fistulizing Crohn's disease is also provided.

    • Ole Haagen Nielsen
    • Gerhard Rogler
    • Ole Østergaard Thomsen
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 6, P: 92-106