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Showing 1–2 of 2 results
Advanced filters: Author: "Gerjan J. Navis" Clear advanced filters

  • Blockade of the renin-angiotensin-aldosterone system (RAAS) is a standard treatment for patients with chronic kidney disease (CKD). Intensive strategies with single-agent or dual-agent RAAS blockade have been used to reduce proteinuria and blood pressure in these patients. This Review discusses strategies for improving the long-term outcomes of patients with CKD treated with RAAS blockade, focusing on the effects of combined low-dietary sodium intake and RAAS-blockade on the risk of renal and cardiovascular outcomes.

    • Hiddo J. Lambers Heerspink
    • Martin H. de Borst
    • Gerjan J. Navis
    Reviews
    Nature Reviews Nephrology
    Volume: 9, P: 112-121

  • New data from Ahmed et al. show that discharge prescriptions for renin–angiotensin–aldosterone inhibitor therapy are associated with a significant reduction in all-cause mortality in elderly patients with diastolic heart failure and chronic kidney disease (CKD). These observational data support the case for prospective studies of RAAS blockade in patients with CKD and diastolic heart failure.

    • Casper F. M. Franssen
    • Gerjan Navis
    News & Views
    Nature Reviews Nephrology
    Volume: 9, P: 190-192