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Showing 1–2 of 2 results
Advanced filters: Author: "Graham R. Foster" Clear advanced filters

  • Insights into the life cycle of hepatitis C virus (HCV) have facilitated the development of a number of innovative agents. Here, Manns and colleagues discuss the obstacles in current HCV management, the key challenges for new HCV antivirals and potential future therapeutic options.

    • Michael P. Manns
    • Graham R. Foster
    • Michael Houghton
    Reviews
    Nature Reviews Drug Discovery
    Volume: 6, P: 991-1000

  • Interferons (IFNs) provide fundamental cellular defence mechanisms against viral infections and cancer. On the 50th anniversary of the discovery of IFNs, the authors provide a comprehensive overview of IFN biology, human therapeutic applications and potential drug targets within the IFN system.

    • Ernest C. Borden
    • Ganes C. Sen
    • George R. Stark
    Reviews
    Nature Reviews Drug Discovery
    Volume: 6, P: 975-990