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Showing 1–2 of 2 results
Advanced filters: Author: "Hakon Hakonarson" Clear advanced filters
  • A new study in humans links genetic variants associated with schizophrenia to changes in the expression of two genes, arsenite methyltransferase (AS3MT) and BLOC-1 related complex subunit 7 (BORCS7). Subsequent investigations provide compelling evidence that AS3MT is involved in the etiology of schizophrenia.

    • Patrick Sleiman
    • Hakon Hakonarson
    News & Views
    Nature Medicine
    Volume: 22, P: 583-584
  • Analytical methods that use knowledge of biological pathways are being developed to extract more information from genome-wide association studies and to guide follow-up studies. This Review discusses the use of pathway-based analysis, the available tools, statistical considerations and directions for future improvements.

    • Kai Wang
    • Mingyao Li
    • Hakon Hakonarson
    Reviews
    Nature Reviews Genetics
    Volume: 11, P: 843-854