In recent years, the interactions between viruses and cellular metabolism have become a topic of great interest. Viral infections that disrupt liver function can be accompanied by changes in iron homeostasis, and iron loading of the liver can exacerbate chronic viral disease. Here, Hal Drakesmith and Andrew Prentice consider some examples of how viruses such as HIV-1, hepatitis C virus and arenaviruses manipulate cellular iron metabolism.
- Hal Drakesmith
- Andrew Prentice
