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Showing 1–7 of 7 results
Advanced filters: Author: "Hamida Hammad" Clear advanced filters

  • The activation of the Notch4–Wnt–GDF15 axis in induced regulatory T (Treg cells) dampens their immunoregulatory function and turns them into TH2 and TH17 cytokine producers, allowing them to maintain ongoing allergic asthma.

    • Hamida Hammad
    • Bart N. Lambrecht
    News & Views
    Nature Immunology
    Volume: 21, P: 1313-1314

  • Lambrecht and Hammad discuss how microbial diversity or dysbiosis influences epithelial barrier tissues and the impact of such interactions on the development of allergic disease.

    • Bart N Lambrecht
    • Hamida Hammad
    Reviews
    Nature Immunology
    Volume: 18, P: 1076-1083

  • Asthma is typically thought to be a consequence of overreactive type II responses. In this Focus Review, Lambrecht and Hammad discuss the latest thinking on the etiology of asthma and the importance of alternative mechanisms such as ILC2, TH9 and TH17 cells.

    • Bart N Lambrecht
    • Hamida Hammad
    Reviews
    Nature Immunology
    Volume: 16, P: 45-56

  • Here, the authors review the expression patterns and function of Fc receptors for IgG (FcγRs) on conventional dendritic cells (DCs), monocyte-derived DCs, plasmacytoid DCs and macrophages in the steady state and at sites of inflammation. They also discuss emerging concepts and areas that require further investigation.

    • Martin Guilliams
    • Pierre Bruhns
    • Bart N. Lambrecht
    Reviews
    Nature Reviews Immunology
    Volume: 14, P: 94-108

  • In addition to providing a physical barrier, epithelial cells have a role in initiating and maintaining allergic responses to inhaled allergens. As discussed in this Review, epithelial cells can influence the polarization of lung dendritic cells and are themselves influenced by innate and adaptive immune responses during allergic inflammation.

    • Hamida Hammad
    • Bart N. Lambrecht
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 193-204