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Showing 1–3 of 3 results
Advanced filters: Author: "Harris Wang" Clear advanced filters

  • The use of marker coselection in combination with multiplex automated genome engineering (MAGE) is reported to improve the efficiency of engineered changes in bacterial genomes. The authors use the method to insert twelve 20-base-pair T7 promoters to control indirubin and indigo production.

    • Harris H Wang
    • Hwangbeom Kim
    • George M Church
    Research
    Nature Methods
    Volume: 9, P: 591-593

  • Risk assessment for the development of antibiotic resistance against a new drug candidate is of paramount importance in preclinical development. In this Opinion article, Sommeret al. propose a new preclinical paradigm for the prediction of antibiotic resistance.

    • Morten O. A. Sommer
    • Christian Munck
    • Dan I. Andersson
    Reviews
    Nature Reviews Microbiology
    Volume: 15, P: 689-696