Samuel, Miyaoka et al. investigate the changes in the molecular composition of lipid droplets inside HuH7 cells and its relation to the physiological state of the cell, using Raman spectroscopy and multivariate curve resolution. This study underscores the importance of separation of spectral components in semi-quantitative molecular profiling of living cells.
- Ashok Zachariah Samuel
- Rimi Miyaoka
- Haruko Takeyama