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Showing 1–8 of 8 results
Advanced filters: Author: "Harvey Lodish" Clear advanced filters

  • Long non-coding RNAs (lncRNAs) have important roles in many physiological and pathological processes. The authors of this Review focus on the endocrine system and discuss the involvement of lncRNAs in the development and function of various endocrine organs, as well as the associations of lncRNAs with endocrine diseases such as diabetes mellitus and endocrine cancers.

    • Marko Knoll
    • Harvey F. Lodish
    • Lei Sun
    Reviews
    Nature Reviews Endocrinology
    Volume: 11, P: 151-160

  • Knipe and Cliffe review the mechanisms that underlie the switch from a lytic to a latent infection in the widespread pathogen herpes simplex virus (HSV). They propose a new model in which an epigenetic switch determines whether a lytic or a latent infection occurs and discuss viral functions that might regulate chromatin assembly on the HSV genome and effect this epigenetic switch.

    • David M. Knipe
    • Anna Cliffe
    Reviews
    Nature Reviews Microbiology
    Volume: 6, P: 211-221

  • Proteins of the Fanconi anaemia pathway are master regulators of genomic integrity through their interactions with other DNA repair pathways to repair interstrand crosslinks, stabilize replication forks and regulate cytokinesis.

    • Raphael Ceccaldi
    • Prabha Sarangi
    • Alan D. D'Andrea
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 17, P: 337-349

  • Vertebrate cell volume is controlled to maintain homeostasis. Volume adjustment is achieved by regulating transmembrane transport of ions and small organic osmolytes through diverse transporters and channels (including volume regulated anion channels (VRACs)), which are also implicated in other physiological processes such as metabolite transport and apoptosis, as well as in pathology.

    • Thomas J. Jentsch
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 17, P: 293-307