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Showing 1–3 of 3 results
Advanced filters: Author: "Hermann Haller" Clear advanced filters

  • Glomerular hyperfiltration has long been thought of as indicative of progression to albuminuria and nephropathy in type 1 diabetes mellitus. However, a new study supports other research in the past few years that has highlighted flaws in this model for kidney disease pathogenesis in type 1 diabetes mellitus.

    • Christos Chatzikyrkou
    • Hermann Haller
    News & Views
    Nature Reviews Endocrinology
    Volume: 8, P: 385-386

  • After becoming established as a therapy for various anemic states, wider uses—including cardiovascular therapy—are being explored for erythropoietin. The possible mechanisms for actions in the cardiovascular and renal systems are explored in this Review, showing that the therapeutic benefits of this cytokine seem much broader than initially anticipated.

    • Danilo Fliser
    • Ferdinand H Bahlmann
    • Hermann Haller
    Reviews
    Nature Clinical Practice Cardiovascular Medicine
    Volume: 3, P: 563-572

  • Micro (mi)RNAs are short, noncoding nucleotides that target and regulate messenger RNA at the post-transcriptional level. In this Review, Lorenzen and colleagues discuss the generation and function of miRNAs as well as their role in chronic kidney diseases such as diabetic nephropathy and hypertensive kidney disease. The potential of miRNA therapeutics for kidney diseases will also be discussed.

    • Johan M. Lorenzen
    • Hermann Haller
    • Thomas Thum
    Reviews
    Nature Reviews Nephrology
    Volume: 7, P: 286-294