The discovery that IgG4 autoantibodies against node of Ranvier proteins are linked to distinct subsets of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) represents a key advance in our understanding of the chronic inflammatory neuropathies (CINs). Here, Querol and colleagues discuss the clinical implications of these autoantibodies in patients with CIDP and other immune-mediated neuropathies.
- Luis Querol
- Jérôme Devaux
- Isabel Illa