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Showing 1–7 of 7 results
Advanced filters: Author: "J Ryan" Clear advanced filters

  • Squares may be unfashionable, but for electronic circuitry no other shape will do. A method for making square arrays of polymeric nanoparticles could herald the next generation of miniature silicon chips.

    • Anthony J. Ryan
    News & Views
    Nature
    Volume: 456, P: 334-336

  • Network analyses of protein–protein, genetic and drug–gene interactions have typically been limited to analyses at the whole-protein and whole-gene levels. This Review discusses how high-resolution network analyses at the domain and residue levels are providing valuable insights into diverse research fields that range from structural biology to human disease.

    • Colm J. Ryan
    • Peter Cimermančič
    • Nevan J. Krogan
    Reviews
    Nature Reviews Genetics
    Volume: 14, P: 865-879

  • The pathophysiology of heart failure is complex, but mitochondrial dysfunction is an emerging therapeutic target to improve cardiac function. In this Consensus Statement, insights into the mechanisms of mitochondrial dysfunction in heart failure are presented, along with an overview of emerging treatments with the potential to improve the function of the failing heart by targeting mitochondria.

    • David A. Brown
    • Justin B. Perry
    • Mihai Gheorghiade
    ReviewsOpen Access
    Nature Reviews Cardiology
    Volume: 14, P: 238-250