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Showing 1–16 of 16 results
Advanced filters: Author: "J. Davis" Clear advanced filters

  • This Review outlines the molecular basis of nongenomic mechanisms of thyroid hormone action. Davis and colleagues also discuss the possible physiological or pathophysiological consequences of these actions, as well as the interactions between nongenomic and genomic effects of thyroid hormone.

    • Paul J. Davis
    • Fernando Goglia
    • Jack L. Leonard
    Reviews
    Nature Reviews Endocrinology
    Volume: 12, P: 111-121

  • Depression ruins the lives of millions of people, causing dysphoria and anguish. New findings in rodents and human brain shed light on the mechanisms of this disease, uncovering a phosphatase as a new target to treat depressive behaviors (pages 1328–1332).

    • Schahram Akbarian
    • Roger J Davis
    News & Views
    Nature Medicine
    Volume: 16, P: 1187-1188

  • It is possible — and crucial — to green the building blocks of the modern world.

    • Paul Fennell
    • Justin Driver
    • Steven J. Davis
    Comments & Opinion
    Nature
    Volume: 603, P: 574-577

  • The observation of path dependence in the response of a superfluid to stirring promises potential applications in precision rotation sensing, and provides a test bed for microscopic theories of ultracold atomic gases. See Letter p.200

    • Matthew J. Davis
    • Kristian Helmerson
    News & Views
    Nature
    Volume: 506, P: 166-167

  • The identification of gene-regulatory polymorphisms that influence cancer susceptibility can identify key oncogenic pathways. A new study links a germline variant to Ewing sarcoma disease susceptibility and EWSR1-FLI1–mediated gene activation.

    • Nicholas C Gomez
    • Ian J Davis
    News & Views
    Nature Genetics
    Volume: 47, P: 964-965

  • Interleukin 2 (IL-2) and IL-15 use receptors with the same signaling subunits. New structural data show that the signaling complexes they form are topologically nearly identical, which suggests that other factors are responsible for the distinct signaling properties of these complexes.

    • Shinji Ikemizu
    • Mami Chirifu
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 13, P: 1141-1142

  • Integrated assessment models show that, without new climate policies, abundant supplies of natural gas will have little impact on greenhouse-gas emissions and climate change. See Letter p.482

    • Steven J. Davis
    • Christine Shearer
    News & Views
    Nature
    Volume: 514, P: 436-437

  • Acute inhibition of the regulatory kinase Csk reveals additional checkpoints for full activation of thymocytes via the T cell antigen receptor.

    • Michael L Dustin
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 15, P: 136-137

  • Recent advances in microscopy have enabled imaging of cell surface receptors at ever higher resolutions. A report using the latest technology now provides evidence that the T cell antigen receptor and the adaptor Lat are confined to small islands, which cluster together after triggering of the T cell antigen receptor.

    • P Anton van der Merwe
    • Paul D Dunne
    • Simon J Davis
    News & Views
    Nature Immunology
    Volume: 11, P: 51-52

  • Brachytherapy offers an excellent treatment option for definitive and salvage treatment of prostate cancer, with excellent oncological outcomes, limited toxic effects, and good quality of life for patients. However, use of prostate brachytherapy has been declining. In this comprehensive Review, Zaorsky and colleagues consider the evolution of brachytherapy from its inception to contemporary practice, from historical background to current indications and contraindications, underlying radiophysics and technical aspects, cost, and clinical outcomes.

    • Nicholas G. Zaorsky
    • Brian J. Davis
    • Eric M. Horwitz
    Reviews
    Nature Reviews Urology
    Volume: 14, P: 415-439

  • Tumor necrosis factor is a key cytokine in the pathogenesis of ankylosing spondylitis. As discussed in this Review, data from randomized controlled trials show that anti-tumor-necrosis-factor agents can control symptoms effectively and possibly prevent the progression of this chronic inflammatory disorder.

    • Cailin Henderson
    • John C Davis
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 2, P: 211-218