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Showing 1–13 of 13 results
Advanced filters: Author: "J. Wilson" Clear advanced filters

  • The timing of seasonal events such as flowering and migration is changing as the climate warms, reshuffling the order in which such events take place each year. Now research sheds light on the causes of changes in the timing of butterfly emergence.

    • Robert J. Wilson
    • David B. Roy
    News & Views
    Nature Climate Change
    Volume: 1, P: 101-102

  • Two readily accessible synthetic building blocks are shown to form a quadruply hydrogen-bonded heterodimer that exhibits exceptional stability and offers new opportunities for the construction of supramolecular assemblies and polymers.

    • Andrew J. Wilson
    News & Views
    Nature Chemistry
    Volume: 3, P: 193-194

  • Diagnosing disease states relies on sensing imbalances in the quantities of markers present in biological fluids. Now a biologically compatible gold nanoparticle sensing-system that detects proteins in serum has been developed, offering great potential for medical diagnostics.

    • Andrew J. Wilson
    News & Views
    Nature Chemistry
    Volume: 1, P: 429-430

  • Mahlon C. Kennicutt II, Steven L. Chown and colleagues outline the most pressing questions in southern polar research, and call for greater collaboration and environmental protection in the region.

    • Mahlon C. Kennicutt
    • Steven L. Chown
    • William J. Sutherland
    Comments & Opinion
    Nature
    Volume: 512, P: 23-25

  • Topographic variations result in microclimatic heterogeneity that can substantially reduce extinction risk from climate change, according to a study of 430 climate-threatened and range-declining species in England.

    • Andrew J. Suggitt
    • Robert J. Wilson
    • Ilya M. D. Maclean
    Research
    Nature Climate Change
    Volume: 8, P: 713-717

  • Advances in whole-genome sequencing have enabled within-host genome evolution to be studied with unprecedented detail. In this Review article, Didelot, Wilson and colleagues discuss how these studies have altered our view of host adaptation and antibiotic resistance during bacterial infection.

    • Xavier Didelot
    • A. Sarah Walker
    • Daniel J. Wilson
    Reviews
    Nature Reviews Microbiology
    Volume: 14, P: 150-162

  • This Review sets out the emerging potential of next-generation sequencing in the context of clinical microbiology. Using bacterial genome sequencing as an example, the authors discuss the options and challenges for species identification, testing for virulence and drug resistance and monitoring outbreaks.

    • Xavier Didelot
    • Rory Bowden
    • Derrick W. Crook
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 601-612

  • α-Helix-mediated protein–protein interactions (PPIs) play a key role in the development of numerous infection and disease states. Modulating such interactions offers considerable therapeutic potential, however, identifying suitable inhibitors has proved challenging. This Review highlights recent and generic approaches for designing inhibitors of helix-mediated PPIs.

    • Valeria Azzarito
    • Kérya Long
    • Andrew J. Wilson
    Reviews
    Nature Chemistry
    Volume: 5, P: 161-173

  • Neurological diseases that result from an underlying genetic mutation or from acquired genetic and/or epigenetic changes are prevalent in the population, and might be amenable to gene therapy. In this Review, Simonato et al. discuss new developments in gene therapy vector design and delivery for the treatment of neurological diseases, including sensorineural disorders, Parkinson disease and epilepsy. The authors also outline the most promising therapeutic approaches to date.

    • Michele Simonato
    • Jean Bennett
    • Joseph C. Glorioso
    Reviews
    Nature Reviews Neurology
    Volume: 9, P: 277-291

  • Ligand-directed protein labeling allows selective modification of native proteins but typically requires stoichiometric quantities of the labeling agent. Here a substoichiometric quantity of a peptide probe bound to a photocatalyst allows selective labeling of a target protein Cys residue in the presence of structurally similar proteins.

    • Hester A. Beard
    • Jacob R. Hauser
    • Robin S. Bon
    ResearchOpen Access
    Communications Chemistry
    Volume: 2, P: 1-9