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Showing 1–4 of 4 results
Advanced filters: Author: "JANET ROWLEY" Clear advanced filters

  • Geneticist who discovered that broken chromosomes cause cancer.

    • Brian J. Druker
    Comments & Opinion
    Nature
    Volume: 505, P: 484

  • BAP1 is a deubiquitylase that is associated with multiprotein complexes that regulate key cellular pathways. Recent findings have indicated that germlineBAP1mutations might cause a novel cancer syndrome. Michele Carbone and colleagues discuss the evidence for this.

    • Michele Carbone
    • Haining Yang
    • Giovanni Gaudino
    Reviews
    Nature Reviews Cancer
    Volume: 13, P: 153-159

  • Epigenetic modifications, including DNA methylation and histone modifications, as well as microRNAs, contribute to the development of acute leukaemias. This Review describes the current understanding of epigenetic changes (including microRNA regulation) in acute leukaemias, with a particular focus on those characterized by balanced chromosomal aberrations.

    • Jianjun Chen
    • Olatoyosi Odenike
    • Janet D. Rowley
    Reviews
    Nature Reviews Cancer
    Volume: 10, P: 23-36