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Showing 1–5 of 5 results
Advanced filters: Author: "Jacek Krol" Clear advanced filters

  • Injured mouse retinal ganglion cells, upon a combination of treatments, can regrow their axons along the entire optic pathway and re-establish connections with their correct brain targets. This can partially restore function.

    • Jacek Krol
    • Botond Roska
    News & Views
    Nature Neuroscience
    Volume: 19, P: 983-984

  • The mammalian retina is a modular brain region, in which cell layers are of uniform thickness but the molecular mechanism controlling this process is not well understood. Here the authors identify a regulatory network consisting of the long noncoding RNA Rncr4, RNA helicase Ddx3x and miR-183/96/182 that controls the even distribution of cells across layers.

    • Jacek Krol
    • Ilona Krol
    • Witold Filipowicz
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13

  • The cellular crosstalk between different classes of regulatory noncoding RNAs has reached a new spatial dimension. Jiang et al. reveal an essential role of a nuclear-paraspeckle-organizing long noncoding RNA and its protein partners in regulating the first steps of microRNA biogenesis.

    • Jacek Krol
    News & Views
    Nature Structural & Molecular Biology
    Volume: 24, P: 783-784

  • MicroRNAs are post-transcriptional regulatory molecules that control many developmental and cellular processes. Recent studies have revealed that microRNAs themselves are subject to sophisticated control at various levels, including biogenesis, function and decay. Such regulation greatly contributes to the specific functions of microRNAs.

    • Jacek Krol
    • Inga Loedige
    • Witold Filipowicz
    Reviews
    Nature Reviews Genetics
    Volume: 11, P: 597-610