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Showing 1–4 of 4 results
Advanced filters: Author: "James Smith" Clear advanced filters

  • Goudreault et al. investigate the role of Afadin downstream of RAS GTPases, substantiating this cell adhesion protein as a true RAS effector that couples its activation to cell polarity through the Scribble protein.

    • Marilyn Goudreault
    • Valérie Gagné
    • Matthew J. Smith
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17

  • Several rearrangements of the MLL gene are associated with acute leukemia, including the fusion of MLL with a RAS effector protein, AF6. Here the authors show that the truncated AF6 can induce AF6-MLL dimerization and drive its oncogenic activity.

    • Matthew J. Smith
    • Elizabeth Ottoni
    • Mitsuhiko Ikura
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13

  • As more startups share competitive business information in their search for partners within big pharma or biotech, what legal protections are available if their intellectual property is infringed upon?

    • Steven A Bogen
    • James M Smith
    • John L DuPré
    Comments & Opinion
    Bioentrepreneur
    P: 1-3