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Advanced filters: Author: "Jan Maarten Wit" Clear advanced filters

  • In this Review, Jeffrey Baron and colleagues explore the latest discoveries in the molecular and cell biology of childhood growth and in the clinical genetics of childhood growth disorders. These findings challenge the established theory that childhood growth is primarily controlled by growth hormone and insulin-like growth factor 1, leading the authors to suggest a broader framework for understanding linear growth disorders.

    • Jeffrey Baron
    • Lars Sävendahl
    • Ola Nilsson
    Reviews
    Nature Reviews Endocrinology
    Volume: 11, P: 735-746

  • After short introductions into the physiology of aromatase and chemical characteristics of aromatase inhibitors, this Review focuses on the efficacy and safety of aromatase inhibitors in the pediatric population, in particular for the treatment of hyperestrogenism, hyperandrogenism, pubertal gynecomastia, and short stature and/or delayed puberty.

    • Jan M. Wit
    • Matti Hero
    • Susan B. Nunez
    Reviews
    Nature Reviews Endocrinology
    Volume: 8, P: 135-147