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Showing 1–3 of 3 results
Advanced filters: Author: "Jane Worthington" Clear advanced filters

  • Jane Worthington and colleagues use a high-density genotyping chip to identify new susceptibility loci for rheumatoid arthritis and examine genetic overlap with other autoimmune diseases. Their results increase the number of confirmed rheumatoid arthritis risk loci in individuals of European ancestry and refine the location of many previously identified association signals to single genes.

    • Steve Eyre
    • John Bowes
    • Jane Worthington
    Research
    Nature Genetics
    Volume: 44, P: 1336-1340

  • This is an issue edsumm for 32. Identification of the Palaeocene/Eocene thermal maximum in a marine sedimentary sequence shows that sea surface temperatures near the North Pole increased from roughly 18 degrees Celsius to over 23 degrees Celsius — such warm values imply the absence of ice and thus exclude the influence of ice-albedo feedbacks on this Arctic warming.

    • Wendy Thomson
    • Anne Barton
    • Jane Worthington
    Research
    Nature Genetics
    Volume: 39, P: 1431-1433

  • This Review discusses the major insights gained from genetic studies in rheumatic diseases, such as genome-wide association studies, meta-analyses, fine-mapping and studies performed across different diseases and/or ethnicities, which have vastly increased our understanding of these diseases.

    • Stephen Eyre
    • Gisela Orozco
    • Jane Worthington
    Reviews
    Nature Reviews Rheumatology
    Volume: 13, P: 421-432