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Showing 1–2 of 2 results
Advanced filters: Author: "Jason D Warren" Clear advanced filters

  • This Case Study describes in detail a case of progranulin-associated frontotemporal lobar degeneration (FTLD). The patient was initially asymptomatic, but developed progressive brain atrophy and deficits on neuropsychological testing before the clinical onset of cognitive impairment. The authors use this case as a springboard to discuss advances in the genetics of FTLD with an emphasis on the importance of serial cognitive testing and neuroimaging.

    • Jonathan D Rohrer
    • Jason D Warren
    • Nick C Fox
    Reviews
    Nature Clinical Practice Neurology
    Volume: 4, P: 455-460

  • Variant forms of Alzheimer disease (AD) exist that are associated with amyloid deposition in the brain but have disparate clinical features. In this Review, the authors argue that selective vulnerability of a core functional network could explain the clinical heterogeneity of disease symptoms in atypical AD and other neurodegenerative disorders.

    • Jason D. Warren
    • Phillip D. Fletcher
    • Hannah L. Golden
    Reviews
    Nature Reviews Neurology
    Volume: 8, P: 451-464