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Showing 1–5 of 5 results
Advanced filters: Author: "Jayne A. Franklyn" Clear advanced filters

  • Agranulocytosis is the most severe adverse effect of antithyroid drug therapy. The findings of a novel study from Japan suggest that this complication occurs more frequently if higher rather than lower starting doses of the thionamide drug methimazole are prescribed. Has the time come to reassess current therapy regimens?

    • Jayne A. Franklyn
    News & Views
    Nature Reviews Endocrinology
    Volume: 5, P: 592-594

  • Subclinical hyperthyroidism is a common biochemical finding, characterized by low levels of serum TSH but normal serum T4 and T3levels. Potential adverse consequences include increased risk of atrial fibrillation and death from vascular diseases. Whether the evidence for harm associated with subclinical hyperthyroidism is sufficient to drive the need for treatment is discussed.

    • Jayne A Franklyn
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 4, P: 550-551