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Showing 1–5 of 5 results
Advanced filters: Author: "Jeffrey Gordon" Clear advanced filters

  • Ley, Gordon and colleagues have analysed and compared published sequences of bacterial communities from humans with both free-living communities and those that are associated with diverse animals. They conclude that gut-associated microbiotas are profoundly different from other free-living microbiotas, and call for widespread sampling of the human gut microbiota to study how different cultures, lifestyles and technologies are impacting on the biodiversity within these fascinating communities.

    • Ruth E. Ley
    • Catherine A. Lozupone
    • Jeffrey I. Gordon
    Research
    Nature Reviews Microbiology
    Volume: 6, P: 776-788

  • Viruses are the most diverse and uncharacterized components of all the major ecosystems on Earth, including that within the mammalian gut. Here, Gordon and colleagues review our current understanding of the diversity and ecology of the bacteriophages present in the human gut and discuss how an improved understanding of phage dynamics could revitalize phage therapy.

    • Alejandro Reyes
    • Nicholas P. Semenkovich
    • Jeffrey I. Gordon
    Reviews
    Nature Reviews Microbiology
    Volume: 10, P: 607-617

  • Gut microbes act as an environmental factor that affects an individual's physiology and metabolism, particularly in the context of obesity and its related metabolic disorders. This Review highlights how gut microbes alter the expression of genes involved in the development of obesity and inflammation and focuses on the potential role of specific nutrients that target the gut microbiota.

    • Nathalie M. Delzenne
    • Audrey M. Neyrinck
    • Patrice D. Cani
    Reviews
    Nature Reviews Endocrinology
    Volume: 7, P: 639-646

  • Histone mRNAs, the only cellular mRNAs that are not polyadenylated, end in a conserved stem–loop that performs the functions of the poly(A) tail in mRNA metabolism and that is required for cell-cycle regulation and regulating the balance of the production of variant and canonical histones.

    • William F. Marzluff
    • Eric J. Wagner
    • Robert J. Duronio
    Reviews
    Nature Reviews Genetics
    Volume: 9, P: 843-854

  • In recent years, the composition of the gut microbiome has become the subject of intensive study. In this Review, Spor, Koren and Ley describe how host genetics and the environment shape the gut microbiome, both in health and in chronic disease.

    • Aymé Spor
    • Omry Koren
    • Ruth Ley
    Reviews
    Nature Reviews Microbiology
    Volume: 9, P: 279-290