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Showing 1–4 of 4 results
Advanced filters: Author: "Jeffrey W. Pollard" Clear advanced filters

  • The homeostatic roles of macrophages in tissue development and maintenance are discussed, and insights are provided into how dysregulation of these primitive functions can be subverted in chronic diseases such as cancer and obesity to contribute to pathology.

    • Jeffrey W. Pollard
    Reviews
    Nature Reviews Immunology
    Volume: 9, P: 259-270

  • In addition to avoiding immune attack in the primary tumour, metastatic cancer cells can harness suppressive immune cells to help promote and protect them from immune surveillance as they travel from the primary tumour site, through blood or lymphatic vessels, to the metastatic site. Thus, targeting pro-metastatic immune cells may offer new therapeutic strategies for treating the major cause of death from cancer — metastatic disease.

    • Takanori Kitamura
    • Bin-Zhi Qian
    • Jeffrey W. Pollard
    Reviews
    Nature Reviews Immunology
    Volume: 15, P: 73-86

  • Metastatic dissemination and growth at distant sites are influenced by cells of the tumour microenvironment. What roles do these cells have in the underlying processes that determine metastatic growth?

    • Johanna A. Joyce
    • Jeffrey W. Pollard
    Reviews
    Nature Reviews Cancer
    Volume: 9, P: 239-252