This Review discusses the key features of innate lymphoid cells (ILCs), which despite their fairly recent identification have emerged as an important cellular component of the immune system. ILCs can rapidly release effector cytokines and promote protective immunity following infection. However, aberrant activation of ILCs may contribute to immunopathology in allergic and autoimmune diseases.
- Jennifer A. Walker
- Jillian L. Barlow
- Andrew N. J. McKenzie