Next-generation sequencing approaches are becoming increasingly affordable for use in the clinical setting, and have the potential to provide valuable insights into the genetic underpinnings of complex neurological diseases. In this Review, Foo et al. discuss how whole-genome and whole-exome sequencing data can be deciphered, and consider how such data might be used for diagnosis and risk prediction in the neurology clinic.
- Jia-Nee Foo
- Jian-Jun Liu
- Eng-King Tan
