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Showing 1–2 of 2 results
Advanced filters: Author: "Jillian J. Kril" Clear advanced filters

  • In this article, Loy and colleagues examine the case of a woman with frontotemporal dementia who presented in the clinic with complex delusions. Psychosis is considered an unusual early feature of this form of dementia but, when present, can wrongly suggest a diagnosis of schizophrenia. In discussing the case, Loyet al. highlight the clinical features that might assist in the differentiation between these two conditions.

    • Clement T. Loy
    • Jillian J. Kril
    • John R. Hodges
    Reviews
    Nature Reviews Neurology
    Volume: 6, P: 175-179

  • The symptoms and neuropathology of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) can show a high degree of overlap, and few effective treatments exist for these conditions. In this Perspectives article, Ittner and colleagues describe recent failures in the translation of data from mouse models into clinical trials for patients with FTD and/or ALS. The authors summarize the strengths and weaknesses of several available mouse models, and make recommendations for improving future research practice.

    • Lars M. Ittner
    • Glenda M. Halliday
    • Matthew C. Kiernan
    Reviews
    Nature Reviews Neurology
    Volume: 11, P: 360-366