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Showing 1–11 of 11 results
Advanced filters: Author: "Jin Billy Li" Clear advanced filters

  • Using the GTEx data and others, a comprehensive analysis of adenosine-to-inosine RNA editing in mammals is presented; targets of the various ADAR enzymes are identified, as are several potential regulators of editing, such as AIMP2.

    • Meng How Tan
    • Qin Li
    • Jin Billy Li
    Research
    Nature
    Volume: 550, P: 249-254

  • cis-RNA editing quantitative trait loci, which are associated with immunogenic double-stranded RNAs, underlie genome-wide association study variants in common autoimmune and inflammatory diseases.

    • Qin Li
    • Michael J. Gloudemans
    • Jin Billy Li
    Research
    Nature
    Volume: 608, P: 569-577

  • For allele-specific expression and RNA editing studies, targeted RNA sequencing using microfluidic multiplexed PCR (mmPCR-seq) gives robust high-throughput measurements of allelic ratios across the dynamic range of gene expression, even for low-quantity or low-quality RNA.

    • Rui Zhang
    • Xin Li
    • Jin Billy Li
    Research
    Nature Methods
    Volume: 11, P: 51-54

  • A computational framework is reported for the accurate and sensitive identification of RNA editing sites from whole-genome DNA and RNA sequences from the same individual.

    • Gokul Ramaswami
    • Wei Lin
    • Jin Billy Li
    Research
    Nature Methods
    Volume: 9, P: 579-581

  • Highly accurate and sensitive predictions of RNA editing sites can be obtained using RNA sequencing data from multiple individuals or species, without relying on matched genomic DNA sequence. Reanalyzing existing RNA sequencing data in this way greatly expands the catalog of human protein recoding events.

    • Gokul Ramaswami
    • Rui Zhang
    • Jin Billy Li
    Research
    Nature Methods
    Volume: 10, P: 128-132

  • Adenosine-to-inosine (A-to-I) RNA editing plays an important role in neurological functions. Here, by a quantitative trait loci (QTL) mapping approach in 131 Drosophila melanogasterstrains, the authors identify 545 QTLs associated with differences in RNA editing.

    • Gokul Ramaswami
    • Patricia Deng
    • Jin Billy Li
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-9

  • Brain enriched RNA editing of Adenosine-to-Inosine (A-to-I) increases the amount of information encoded in the genome and diversifies the transcriptome. Here the authors discuss how recent technological and analytical developments may facilitate the discovery of RNA editing sites and the understanding of their functions and regulation.

    • Jin Billy Li
    • George M Church
    Reviews
    Nature Neuroscience
    Volume: 16, P: 1518-1522

  • Environmental adaptation is generally studied at the genomic level, but it may also be driven by transcriptional processes. Here, the authors investigate variation in gene expression and RNA editing across diverging populations of Drosophila melanogaster from two microclimates.

    • Arielle L. Yablonovitch
    • Jeremy Fu
    • Jin Billy Li
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14