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Showing 1–4 of 4 results
Advanced filters: Author: "Johannes L. Bos" Clear advanced filters

  • Dishevelled, EGL-10 and pleckstrin (DEP) domains carry out diverse functions by using different binding interfaces with well-defined structural features. It is becoming apparent that DEP domains mainly function in the spatial and temporal control of diverse signal transduction events by interacting with various partners at the plasma membrane.

    • Sarah V. Consonni
    • Madelon M. Maurice
    • Johannes L. Bos
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 15, P: 357-362

  • Many cellular processes are regulated by cyclic nucleotides through their binding to and activation of protein kinase A, protein kinase G, ion channels and Epac. Recent structural insights have advanced our understanding of how cyclic nucleotides might regulate these proteins.

    • Holger Rehmann
    • Alfred Wittinghofer
    • Johannes L. Bos
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 8, P: 63-73