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Showing 1–6 of 6 results
Advanced filters: Author: "John P Neoptolemos" Clear advanced filters
  • A recent trial concluded that preoperative biliary drainage (PBD) in patients with pancreatic head cancer increases complications but is unlikely to change clinical practice. The difference in the outcomes reported was because of excessive complications in the PBD group using plastic stents. We argue that these patients need treatment in regional pancreatic cancer centers using low-occlusion metal stents.

    • John P. Neoptolemos
    • Christopher M. Halloran
    News & Views
    Nature Reviews Clinical Oncology
    Volume: 7, P: 244-246
  • Pancreatic cancer is usually detected at an advanced stage and responds poorly to treatment. In 2010 new insights were gained into understanding the complex biology of pancreatic cancer. Importantly, these insights offer novel opportunities for early diagnosis and treatment of this disease.

    • Eithne Costello
    • John P. Neoptolemos
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 8, P: 71-73
  • Survival in patients with advanced pancreatic cancer is particularly poor, and improvements in diagnosis and treatment are urgently needed. Identification of new biomarkers and targets in pancreatic cancer could enable prediction of treatment response. In this Review, Costello and colleagues describe predictive pancreatic cancer biomarkers as well as novel treatment approaches and future treatment targets.

    • Eithne Costello
    • William Greenhalf
    • John P. Neoptolemos
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 9, P: 435-444