Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: "Jonathan Maelfait" Clear advanced filters

  • In addition to its role in suppressing MDA5 and PKR activation, ADAR1 is a negative regulator of ZPB1-mediated apoptosis and necroptosis, providing insights into the pathology of Aicardi–Goutières syndrome.

    • Richard de Reuver
    • Simon Verdonck
    • Jonathan Maelfait
    Research
    Nature
    Volume: 607, P: 784-789

  • This Review discusses how the study of novel mouse models of human ADAR1 deficiency has led to the identification of the innate immune receptors recognizing endogenous immunostimulatory double-stranded RNA and their respective downstream signalling pathways that induce autoinflammatory pathology.

    • Richard de Reuver
    • Jonathan Maelfait
    Reviews
    Nature Reviews Immunology
    Volume: 24, P: 235-249