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Showing 1–2 of 2 results
Advanced filters: Author: "Jorg Dietrich" Clear advanced filters

  • Brain tumors may harbor small subpopulations of cells that share characteristics of neural stem cells. The use of neural stem cells and progenitor cells as delivery vehicles of molecules toxic to tumors offers a promising experimental treatment strategy. This Review summarizes recent advances in the basic understanding of neural stem cell and cancer-stem-cell biology and the progress towards translating these novel concepts into the clinic.

    • Jörg Dietrich
    • Jaime Imitola
    • Santosh Kesari
    Reviews
    Nature Clinical Practice Oncology
    Volume: 5, P: 393-404

  • Glioblastomas are difficult to treat, and patients have a poor prognosis. Knowledge of the molecular pathogenesis of glioma has launched an era of targeted-therapies, which are discussed in this Review article. Biomarkers, novel trial design, and the identification of molecular subgroups are other advances that are explored here.

    • Shota Tanaka
    • David N. Louis
    • Jorg Dietrich
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 10, P: 14-26