In this Review, Oksenberg and Baranzini examine the field of multiple sclerosis (MS) genetics, focusing on the abundance of data that has been generated from genome-wide association studies. The authors also highlight the challenges that lie ahead in this field, including the need for functional studies to connect the genetic variation observed in patients with the underlying pathophysiology of this condition.
- Jorge R. Oksenberg
- Sergio E. Baranzini